To reach Apulia, the highways are, depending on your point of departure, the A14 Bologna-Taranto and the A16. The main roads that connect the main regional centres are:
- SS16: Foggia, Bari, Brindisi, Lecce, Otranto;
- SS100: Bari-Taranto;
- SS7: Taranto-Brindisi;
- SS613: Brindisi-Lecce;
- SS7 ter: Taranto-Lecce;
- SS101: Lecce-Gallipoli;
- SS275: Maglie-Santa Maria di Leuca.
Useful links for those traveling by car: www.stradeanas.it e www.autostrade.it.